Absolute neutrophil count

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The absolute number of neutrophils (ANC) is a measure of the number of neutrophil granulocytes (also known as polymorphonuclear cells, PMN, polys, granulocytes, segmented neutrophils or segs) present in the blood. Neutrophils are a type of white blood cells that fight infection.

ANC is almost always part of a larger blood panel called a complete blood count. The ANC is calculated from measuring the total number of white blood cells (WBC), usually based on the combined percentage of mature neutrophils (sometimes called "segs," or segmented cells) and the ribbon, which is an immature neutrophil.

Video Absolute neutrophil count

Clinical interests

The reference range for ANC in adults varies by study, but 1500 to 8000 cells per microliter is typical. ANC less than 1500 cells/ÂμL is defined as neutropenia and increases the risk of infection. Neutropenia is a low ANC condition, and the most common condition in which ANC will be measured is chemotherapy regulation for cancer.

Neutrophilia shows an increasing number. While many physicians refer to the presence of neutrophilia as "left shift," this is not appropriate, since the left shift indicates an immature neutrophil form, but neutrophilia refers to the entire neutrophil mass, both mature and immature. Neutrophilia can be an indication:

• Early release of myeloid cells from the bone marrow.
• Leukemoid reaction.

Maps Absolute neutrophil count

Calculation

xmlns ANC = %           n           dan           u           t           r           atau           P           h           yang           yang           s                     %           b           a           n           d           s           )           ÃÆ' -           (           W           B           C           )                          (           100           )                     {\ displaystyle (\% neutrofil \% band) \ kali (WBC) \ lebih (100)}  Â

or

ANC = ( Absolute-Polys Absolute-Bands )

Above, we assume that WBC is given in cells/Ã,ÂμL (or thousands of cells/mL, ie K/mL) such as 8,800 cells/Ã,ÂμL or 8,800 K/mL; if WBC is given in K/Ã,ÂμL (not cell/Ã,ÂμL or K/mL), such as 8.8 K/Ã,ÂμL, you will first convert to cell/Ã,ÂμL by multiplying WBC by 1000.

The ANC unit is a cell per microliter of blood (abbreviated cell/Ã,ÂμL, microliter equals one cubic millimeter because 1,000,000 cubic millimeters equals one liter).

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Range

Source: NCI CTC Toxicity scale Version 4.0 [1]

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Related test

In some cases, the ratio is reported in addition to the amount. This is known as the "I/T ratio".

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References

Source of the article : Wikipedia